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Review
. 2014 Summer;14(2):203-7.

Steroids: pharmacology, complications, and practice delivery issues

William Ericson-Neilsen  1 , Alan David Kaye  2
Affiliations
Review

Steroids: pharmacology, complications, and practice delivery issues

William Ericson-Neilsen et al. Ochsner J. 2014 Summer.

Abstract

Background: Since their identification nearly 80 years ago, steroids have played a prominent role in the treatment of many disease states. Many of the clinical roles of steroids are related to their potent antiinflammatory and immune-modulating properties.

Methods: This review summarizes the basic pharmacology, complications, and practice delivery issues regarding steroids.

Results: Clinically relevant side effects of steroids are common and problematic. Side effects can occur at a wide range of doses and vary depending on the route of administration. The full spectrum of side effects can be present even in patients taking low doses.

Conclusions: Practitioners must be aware that these drugs might exacerbate a preexisting condition or present a new medical condition. Knowledge of the clinical implications of prescribing these agents is critical.

Keywords: Adrenal cortex hormones; diabetes mellitus; drug-related side effects and adverse reactions; glucocorticoids; medication therapy management; mineralocorticoids.

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Conflict of interest statement

The authors have no financial or proprietary interest in the subject matter of this article.

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