Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2013 Dec;13(4):907-13.
doi: 10.4314/ahs.v13i4.7.

A review of the management of perforated duodenal ulcers at a tertiary hospital in south western Nigeria

A C Etonyeaku  1 , E A Agbakwuru  1 , A A Akinkuolie  1 , C A Omotola  1 , A O Talabi  1 , C U Onyia  1 , O A Kolawole  1 , O A Aladesuru  1
Affiliations
Review

A review of the management of perforated duodenal ulcers at a tertiary hospital in south western Nigeria

A C Etonyeaku et al. Afr Health Sci. 2013 Dec.

Abstract

Background: Gastro-duodenal perforations are common and may complicate peptic ulcer disease. Management is often by surgical closure.

Objective: To determine the patterns of presentation and mode of management of duodenal ulcer perforations.

Methods: Retrospective review of patients with duodenal ulcer perforations seen at the Obafemi Awolowo University Teaching Hospital between June 2001 and July 2011. Patients' records were reviewed for demography, duration of disease, probable risk factors, type of surgery and complications. Data obtained was analyzed using SPSS 15.0.

Result: Forty- five patients were reviewed. There were 37 males (82.2%). Mean age was 39.7years (range 15-78years). There were 10 (22.6%) students and 8(17.8%) farmers. NSAIDs abuse (11), previous peptic ulcer disease (2), and no prior dyspeptic symptoms (20) constituted 24.4%, 4.4% and 44.4% respectively of cases. Seven (16%) patients presented less than 24 hours of onset of illness. Forty one perforations (91.1%) involved the first part of duodenum. Twenty two (49%) patients had Graham's omental patch. We had one (2.2%) failed repair and six (13.3%) mortalities.

Conclusion: Late presentation of duodenal ulcer perforation is common with high mortality. Pragmatic surgical intervention with Graham's omentopexy with broad spectrum antibiotics is still commonly practiced.

Keywords: Duodenal ulcers; Nigeria; management; perforations.

PubMed Disclaimer

References

    1. Svanes C. Trends in Perforated Peptic Ulcer: Incidence, Aetiology, Treatment and Prognosis. World J Surg. 2000;24:277–283. - PubMed
    1. Dakubo JC, Naaeder SB, Clegg-Lamptey JN. Gastroduodenal pepetic ulcer perforation. East Afri Med J. 2009;86(3):100–109. - PubMed
    1. Chalya, et al. Clinical profile and outcome of surgical treatment of perforated peptic ulcers in North-western Tanzania: A tertiary hospital experience. World Journal of Emergency Surgery. 2011;6:31. (10pages). Available from: http://www.wjes.org/content/6/1/31. - PMC - PubMed
    1. Gupta S, Kaushik R. The Management of Large perforations of Duodenal Ulcers. BMC Surgery. 2005;5:15. - PMC - PubMed
    1. Hill AG. Management of perforated duodenal ulcer. In: Holzheimer RG, Mannick JA, editors. Surgical Treatment: Evidence-Based and Problem-Oriented. Munich: Zuckschwerdt; Available from: http://www.ncbi.nlm.nih.gov/books/NBK6926/ - PubMed

MeSH terms

LinkOut - more resources