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. 2014 May;8(5-6):E361-3.
doi: 10.5489/cuaj.1692.

Isolated anterior urethral recurrence of prostatic adenocarcinoma

Darren Beiko  1 , Khaled Zaza  2 , Kevin V Power  3 , D Robert Siemens  1 , Alexander H Boag  4
Affiliations

Isolated anterior urethral recurrence of prostatic adenocarcinoma

Darren Beiko et al. Can Urol Assoc J. 2014 May.

Abstract

Isolated anterior urethral metastases from prostate cancer are rare. The pathogenesis of this form of loco-regional recurrence may be related to spread by instrumentation-induced implantation and could potentially then be associated with a better prognosis than metastatic disease secondary to a more malignant phenotype. We report a case of a 68-year-old man with high-risk prostate cancer, diagnosed at transurethral resection of prostate, who was originally treated with combination external beam radiotherapy and hormonal therapy. He re-presented 4 years after his original diagnosis with recurrent gross hematuria and cystourethroscopic biopsies of anterior urethral polyps revealing isolated recurrent prostatic adenocarcinoma. We present our this case and review the literature.

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Figures

Fig. 1.
Fig. 1.
Histology of the bulbous urethral biopsy showed a cribriform pattern of prostatic adenocarcinoma.
Fig. 2.
Fig. 2.
Immunohistochemical stain of the bulbous urethral biopsy was positive for prostate-specific antigen.
See this image and copyright information in PMC

References

    1. Taylor GB, McNeal JE, Cohen RJ. Intraductal carcinoma of the prostate metastatic to the penile urethra: A rare demonstration of two morphologic patterns of tumor growth. Pathology. 1998;30:218–21. doi: 10.1080/00313029800169306. - DOI - PubMed
    1. Blanco Díez A, Ruibal Moldes M, Rodríguez-Rivera García J, et al. Metastasis of prostatic carcinoma to the urethra: Report of a case [in Spanish] Actas Urol Esp. 2003;27:735–8. doi: 10.1016/S0210-4806(03)73006-X. - DOI - PubMed
    1. Subudhi CL, Panda SN, Panigrahi KK. Urethral metastases from carcinoma of prostate. Indian J Cancer. 1994;31:31–3. - PubMed
    1. Koh E, Sekii K, Namiki M, et al. Urethral metastasis from prostatic carcinoma as diagnosed by immunoperoxidase technique using prostate-specific antigen and prostate-specific acid phosphatase. Eur Urol. 1987;13:142–4. - PubMed
    1. Rao MS, Bapna BC, Bhat VN, et al. Multiple urethral metastases from prostatic carcinoma causing urinary retention. Urology. 1977;10:566–7. doi: 10.1016/0090-4295(77)90104-2. - DOI - PubMed

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