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. 2014 Oct;32(8):388-93.
doi: 10.3109/07357907.2014.919308. Epub 2014 Jun 18.

Lung nodule and functional changes in smokers after smoking cessation short-term treatment

Eliana Maci  1 , Francesca Comito, Anna Maria Frezza, Giuseppe Tonini, Aldo Pezzuto
Affiliations

Lung nodule and functional changes in smokers after smoking cessation short-term treatment

Eliana Maci et al. Cancer Invest. 2014 Oct.

Abstract

Background: Tobacco smoke causes lung disfunction and inflammation.

Methods: Twenty-two consecutive smokers with undetermined lung nodules were included. All underwent a baseline imaging, exhaled carbon monoxide level evaluation and spirometry, repeated at three months from smoking cessation therapy.

Results: A significant reduction in size of the lung nodules was reported (p = .037) as a trend in number reduction (p = .11). A significant increase in blood arterial oxygen pressure (p < .0001), heart rate reduction (p < .01), and FEV1 increase (p < .0001) was recorded.

Conclusions: Smoking cessation reduces number and size of lung nodules and improves in lung functionality.

Keywords: High resolution tomography; Lung nodule evolution; Smoking cessation; Tobacco.

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