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. 1989 Jan;9(1):342-4.
doi: 10.1128/mcb.9.1.342-344.1989.

Stability of transcription complexes on class II genes

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Stability of transcription complexes on class II genes

M W Van Dyke et al. Mol Cell Biol. 1989 Jan.

Abstract

Commitment of a TATA box-driven class II gene to transcription requires binding of only one transcription factor, TFIID. Additional factors (TFIIB, TFIIE, and RNA polymerase II) do not remain associated with the TFIID-promoter complex during the course of transcription. This indicates that there are two intermediates along the transcription reaction pathway which may be potential targets for the regulation of gene expression.

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