Stability of transcription complexes on class II genes
- PMID: 2494433
- PMCID: PMC362180
- DOI: 10.1128/mcb.9.1.342-344.1989
Stability of transcription complexes on class II genes
Abstract
Commitment of a TATA box-driven class II gene to transcription requires binding of only one transcription factor, TFIID. Additional factors (TFIIB, TFIIE, and RNA polymerase II) do not remain associated with the TFIID-promoter complex during the course of transcription. This indicates that there are two intermediates along the transcription reaction pathway which may be potential targets for the regulation of gene expression.
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