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. 2014 Apr;7(4):997-1000.
doi: 10.3892/ol.2014.1831. Epub 2014 Jan 28.

Pulmonary sclerosing hemangioma with lymph node metastasis: A case report and literature review

Yasushi Adachi  1 , Koji Tsuta  2 , Ryuji Hirano  3 , Jin Tanaka  3 , Keizo Minamino  4 , Tomohiko Shimo  5 , Susumu Ikehara  6
Affiliations

Pulmonary sclerosing hemangioma with lymph node metastasis: A case report and literature review

Yasushi Adachi et al. Oncol Lett. 2014 Apr.

Abstract

Pulmonary sclerosing hemangioma (SH) is an uncommon benign or low-grade malignant tumor. Multicentric SH and SH with lymph node metastasis have rarely been reported. The present report describes a case of pulmonary SH with lymph node metastasis in a middle-aged female. A nodule was found incidentally in the lower left lung. The patient underwent left lower pulmonary lobectomy and lymph node dissection. Histologically, the nodule demonstrated the characteristic features of SH and one of the resected lymph nodes contained a metastasis of this tumor. Thus, pulmonary SH has the potential to metastasize, a potential not suggested by histological features.

Keywords: lung; lymph node metastasis; middle-aged female; sclerosing hemangioma.

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Figures

Figure 1
Figure 1
Computed tomography scan images of. (A) whole chest and (B) enlarged scan of the tumor.
Figure 2
Figure 2
Macroscopic and microscopic findings. (A) Photograph of the tumor; (B) photograph of the tumor stained with hematoxylin and eosin captured through a magnifying glass; and (C–E) various microscopic features of the tumor (magnification, ×20).
Figure 3
Figure 3
Immunohistological staining with (A) hematoxylin and eosin, (B) anti-napsin A antibody, (C) anti-cytokeratin AE1/AE3 antibody and (D) anti-thyroid transcription factor 1 antibody (magnification, ×20).
Figure 4
Figure 4
Lymph node metastasis of sclerosing hemangioma. (A) Photograph showing a mediastinal lymph node from the patient. Microscopic evaluation of the metastatic area with (B) hematoxylin and eosin staining and (C) staining with anti-thyroid transcription factor 1 antibody.
See this image and copyright information in PMC

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