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. 2014 Jun 2:6:ecurrents.outbreaks.4635a54dbffba2156fb2fd76dc49f65e.
doi: 10.1371/currents.outbreaks.4635a54dbffba2156fb2fd76dc49f65e.

Imported zika virus infection from the cook islands into australia, 2014

Affiliations

Imported zika virus infection from the cook islands into australia, 2014

Alyssa T Pyke et al. PLoS Curr. .

Abstract

A female resident of Townsville, Queensland, Australia has been diagnosed with Zika virus infection following a recent trip to the Cook Islands. An initial serum sample collected in March, 2014 was positive by two separate Zika virus TaqMan real-time RT-PCRs and a pan-Flavivirus RT-PCR. Nucleotide sequencing and phylogenetics of the complete Cook Islands Zika virus envelope gene revealed 99.1% homology with a previous Cambodia 2010 sequence within the Asian lineage. In addition, IgG and IgM antibody seroconversions were detected between paired acute and convalescent phase sera using recombinant Zika virus serology assays. This is the first known imported case of Zika virus infection into northern Queensland where the potential mosquito vector Aedes aegypti is present and only the second such reported case diagnosed within Australia.

Keywords: arbovirus; infectious disease.

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Figures

Maximum likelihood phylogenetic tree based on complete E gene nucleic acid sequence constructed using MEGA (www.megasoftware.net) with bootstrap support (1,000 replications).
Maximum likelihood phylogenetic tree based on complete E gene nucleic acid sequence constructed using MEGA (www.megasoftware.net) with bootstrap support (1,000 replications).

References

    1. Hayes EB. Zika virus outside Africa. Emerg Infect Dis. 2009 Sep;15(9):1347-50. PubMed PMID:19788800. - PMC - PubMed
    1. Dick GW, Kitchen SF, Haddow AJ. Zika virus. I. Isolations and serological specificity. Trans R Soc Trop Med Hyg. 1952 Sep;46(5):509-20. PubMed PMID:12995440. - PubMed
    1. Haddow AD, Schuh AJ, Yasuda CY, Kasper MR, Heang V, Huy R, Guzman H, Tesh RB, Weaver SC. Genetic characterization of Zika virus strains: geographic expansion of the Asian lineage. PLoS Negl Trop Dis. 2012;6(2):e1477. PubMed PMID:22389730. - PMC - PubMed
    1. Lanciotti RS, Kosoy OL, Laven JJ, Velez JO, Lambert AJ, Johnson AJ, Stanfield SM, Duffy MR. Genetic and serologic properties of Zika virus associated with an epidemic, Yap State, Micronesia, 2007. Emerg Infect Dis. 2008 Aug;14(8):1232-9. PubMed PMID:18680646. - PMC - PubMed
    1. Kwong JC, Druce JD, Leder K. Zika virus infection acquired during brief travel to Indonesia. Am J Trop Med Hyg. 2013 Sep;89(3):516-7. PubMed PMID:23878182. - PMC - PubMed