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Case Reports
. 2013 Oct;2(4):222-4.
doi: 10.4103/2303-9027.121248.

Solitary pancreatic metastasis from renal cell carcinoma 6 years after nephrectomy

Hussein Hassan Okasha  1 , Emad Hamza Al-Gemeie  2 , Reem Ezzat Mahdy  3
Affiliations
Case Reports

Solitary pancreatic metastasis from renal cell carcinoma 6 years after nephrectomy

Hussein Hassan Okasha et al. Endosc Ultrasound. 2013 Oct.

Abstract

Metastatic cancer to the pancreas is rare and accounts for less than 2% of all pancreatic malignancies. Renal cell cancer, malignant melanoma, lung, colon and breast carcinoma are among the few tumors known to metastasize to the pancreas. The pancreas is a rare site of solitary metastasis, but it is often involved in diffuse metastatic disease. We report a case of a female patient with a solitary mass in the neck of the pancreas following right nephrectomy performed 6 years previously for renal cell carcinoma (RCC). An endoscopic ultrasound (EUS) revealed a well-defined lesion in the neck of the pancreas. Patient underwent EUS-guided fine-needle aspiration and cytopathology confirmed the diagnosis of a metastatic RCC. Solitary pancreatic metachronous metastasis from RCC may rarely occur. The interval between nephrectomy and pancreatic metastasis may be long.

Keywords: endoscopic ultrasound-guided fine needle aspiration; renal cell carcinoma; solitary pancreatic metastasis.

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Figures

Figure 1
Figure 1
A well-defined mass at the neck of pancreas as seen by endoscopic ultrasound
Figure 2
Figure 2
The pancreatic mass showing elasticity score 4
Figure 3
Figure 3
Pancreatic mass fine-needle aspiration cytology smear; group of malignant tumor cells having large pleomorphic hyperchromatic nuclei and clear vacuolated cytoplasm, with complete loss of polarity (Papanicolaou, ×HP)
Figure 4
Figure 4
Pancreatic mass fine-needle aspiration cytology, cell block; group of malignant tumor cells having clear cytoplasm beside pancreatic ducts lined by columnar cells having bland basal nuclei (H and E, ×MP)
See this image and copyright information in PMC

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