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Review
. 2014 Nov 15:61:491-9.
doi: 10.1016/j.bios.2014.05.039. Epub 2014 Jun 3.

Brief review of monitoring methods for loop-mediated isothermal amplification (LAMP)

Xuzhi Zhang  1 , Stuart B Lowe  2 , John Justin Gooding  3
Affiliations
Review

Brief review of monitoring methods for loop-mediated isothermal amplification (LAMP)

Xuzhi Zhang et al. Biosens Bioelectron. .

Abstract

The loop-mediated isothermal amplification (LAMP) technique has the potential to revolutionize molecular biology because it allows DNA amplification under isothermal conditions and is highly compatible with point-of-care analysis. To achieve efficient genetic analysis of samples, the method of real-time or endpoint determination selected to monitor the biochemical reaction is of great importance. In this paper we briefly review progress in the development of monitoring methods for LAMP.

Keywords: Biosensor; LAMP; Loop-mediated isothermal amplification; Monitoring methods; Point-of-care analysis.

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