Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Sep 1;2011(9):8.
doi: 10.1093/jscr/2011.9.8.

Incidentally detected squamous cell carcinoma in non-functioning kidney presenting as multi-cystic mass

Sk Mathur  1 , P Rana  1 , S Singh  1 , V Goyal  1 , M Sangwan  1
Affiliations

Incidentally detected squamous cell carcinoma in non-functioning kidney presenting as multi-cystic mass

Sk Mathur et al. J Surg Case Rep. .

Abstract

Squamous cell carcinoma (SCC) of urinary tract is a rarely encountered tumor. The incidence of this tumor is 1.4 per cent of all renal malignancies (1). We present a case of 52 years male with squamous cell carcinoma of renal pelvis, presenting as chronic pyelonephritis transforming the kidney into non-functioning multicystic cavitatory mass without any renal calculi. The case highlights the rarity of tumor in absence of calculi or any other predisposing factor. Moreover, histology of resected specimen detected features of SCC giving importance to careful and exhaustive assessment of specimen and of histologic sections, when there is no suspicion of malignancy clinically.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Tubules showing thyroidisation favouring chronic pylonephritis. (100x H and E stain).
Figure 2
Figure 2
Cyst lined by metaplastic epithelium with focus of malignant squamous cell. (100x H and E stain)
Figure 3
Figure 3
Sheets of malignant squamous cells (400x H and E stain)
See this image and copyright information in PMC

References

    1. Tyagi N, Sharma S, Tyagi SP, Maheshwari V, Nath P, Asharf SM, et al. A histomorphologic and ultrastructural study of the malignant tumors of the renal pelvis. J Postgrad Med 1993;39:197–20 - PubMed
    1. Mizusawa H, Komiyama I, Ueno Y, Maejima T, Kato H. Squamous cell carcinoma in the renal pelvis of a horse shoe kidney. Int J Urol 2004; 11:782–4 - PubMed
    1. Talwar N, Dargan P, Arora MP, Sharma S, Sen AK. Primary squamous cell carcinoma of the renal pelvis masquerading as pyonephrosis: A case report. Indian J Pathol Microbiol 2006;49:418–20 - PubMed
    1. Latham HS, Kay S. Malignant tumors of the renal pelvis. Surg Gynecol Obstet 1974;138:613–22
    1. Li MK, Cheung WL. Squamous cell carcinoma of the renal pelvis. J Urol 1987;138:269–71 - PubMed