MicroRNA therapy for the failing heart
- PMID: 24951666
- DOI: 10.1161/CIRCGENETICS.114.000687
MicroRNA therapy for the failing heart
Keywords: SERCA2a Calcium ATPase; heart failure; miRNA; microRNAs; translational medical research.
Comment on
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Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): a phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum Ca2+-ATPase in patients with advanced heart failure.Circulation. 2011 Jul 19;124(3):304-13. doi: 10.1161/CIRCULATIONAHA.111.022889. Epub 2011 Jun 27. Circulation. 2011. PMID: 21709064 Free PMC article. Clinical Trial.
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Inhibition of miR-25 improves cardiac contractility in the failing heart.Nature. 2014 Apr 24;508(7497):531-5. doi: 10.1038/nature13073. Epub 2014 Mar 12. Nature. 2014. PMID: 24670661 Free PMC article.
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