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Comment

. 2014 Jun;7(3):393-4.

doi: 10.1161/CIRCGENETICS.114.000687.

MicroRNA therapy for the failing heart

Almudena Martinez-Fernandez¹

Affiliations

PMID: 24951666
DOI: 10.1161/CIRCGENETICS.114.000687

Comment

MicroRNA therapy for the failing heart

Almudena Martinez-Fernandez. Circ Cardiovasc Genet. 2014 Jun.

. 2014 Jun;7(3):393-4.

doi: 10.1161/CIRCGENETICS.114.000687.

Author

Almudena Martinez-Fernandez¹

Affiliation

¹ From the Division of Cardiovascular Diseases and Center for Regenerative Medicine, Mayo Clinic, Rochester, MN. MartinezFernandez.Almudena@mayo.edu.

PMID: 24951666
DOI: 10.1161/CIRCGENETICS.114.000687

No abstract available

Keywords: SERCA2a Calcium ATPase; heart failure; miRNA; microRNAs; translational medical research.

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Comment on

Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): a phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum Ca2+-ATPase in patients with advanced heart failure.
Jessup M, Greenberg B, Mancini D, Cappola T, Pauly DF, Jaski B, Yaroshinsky A, Zsebo KM, Dittrich H, Hajjar RJ; Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID) Investigators. Jessup M, et al. Circulation. 2011 Jul 19;124(3):304-13. doi: 10.1161/CIRCULATIONAHA.111.022889. Epub 2011 Jun 27. Circulation. 2011. PMID: 21709064 Free PMC article. Clinical Trial.
Inhibition of miR-25 improves cardiac contractility in the failing heart.
Wahlquist C, Jeong D, Rojas-Muñoz A, Kho C, Lee A, Mitsuyama S, van Mil A, Park WJ, Sluijter JP, Doevendans PA, Hajjar RJ, Mercola M. Wahlquist C, et al. Nature. 2014 Apr 24;508(7497):531-5. doi: 10.1038/nature13073. Epub 2014 Mar 12. Nature. 2014. PMID: 24670661 Free PMC article.

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