Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2014 Apr 15;7(4):799-808.
eCollection 2014.

Therapeutics role of olive fruits/oil in the prevention of diseases via modulation of anti-oxidant, anti-tumour and genetic activity

Affiliations
Review

Therapeutics role of olive fruits/oil in the prevention of diseases via modulation of anti-oxidant, anti-tumour and genetic activity

Arshad H Rahmani et al. Int J Clin Exp Med. .

Abstract

The current mode of treatment for various diseases is based on synthetic drugs are effective but they show adverse effect and also alter the genetic and metabolic activity. Moreover, some drugs prepared from plants and their constituents show potentiality with more efficacy than synthetic agents used in clinical therapy. Earlier report has shown that regular consumption of fruits and vegetables is strongly related with reduced risk of developing various diseases. Several epidemiological studies has shown that, the incidence heart disease and cancers is lowest in the Mediterranean basin as compared to the part of the world because of their diet rich in olives and olive products. Olives are commonly consumed in Mediterranean and Arabian Peninsula and also have been documented in Holy Quran and modern scientific literatures. Earlier studies have shown that, the constituents from olive such as oleuropein, squalene and hydroxytyrosol modulate the genes functions and other activities. In this review, the medicinal value of olives and their constituents are summarized in terms of therapeutic approach in the diseases management through regulation of various activities.

Keywords: Olive; anti-tumour activity; antioxidant activity; diseases control.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Olive and their constituents show a vital role in the diseases management.
Figure 2
Figure 2
Olive and their constituents show a significant effect in regulation of inflammatory process via modulation of genes.
Figure 3
Figure 3
Olive and their constituents play a role in cancer prevention via modulation of genes.

Similar articles

Cited by

References

    1. Aldebasi YH, Aly SM, Rahmani AH. Therapeutic implications of curcumin in the prevention of diabetic retinopathy via modulation of anti-oxidant activity and genetic pathways. Int J Physiol Pathophysiol Pharmacol. 2013;5:194–202. - PMC - PubMed
    1. Abdelmeguid NE, Fakhoury R, Kamal SM, Al Wafai RJ. Effects of Nigella sativa and thymoquinone on biochemical and subcellular changes in pancreatic β-cells of streptozotocin-induced diabetic rats. J Diabetes. 2010;2:256–66. - PubMed
    1. Salim EI, Fukushima S. Chemopreventive potential of volatile oil from black cumin (Nigella SativaL. ) seeds against rat colon carcinogenesis. Nutr Cancer. 2003;45:195–202. - PubMed
    1. Abdu SB. The protective role of Ajwa date against the hepatotoxicity induced by Ochratoxin A. Egyp J Nat Tox. 2011;8:1–15.
    1. Ragab AR, Elkablawy MA, Sheik BY, Baraka HN. Antioxidant and tissueprotectivestudies on Ajwa extract: dates from Al Madinah Al-Monwarah, SaudiaArabia. J Environ Anal Toxicol. 2013;3:2161–0525.

LinkOut - more resources