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. 2012 Mar 6;3(1):163-72.
doi: 10.3390/jfb3010163.

Development of ti-coated ferromagnetic needle, adaptable for ablation cancer therapy by high-frequency induction heating

Takashi Naohara  1 , Hiromichi Aono  2 , Tsunehiro Maehara  3 , Hideyuki Hirazawa  4 , Shinya Matsutomo  5 , Yuji Watanabe  6
Affiliations

Development of ti-coated ferromagnetic needle, adaptable for ablation cancer therapy by high-frequency induction heating

Takashi Naohara et al. J Funct Biomater. .

Abstract

To develop a novel ablation therapy for human solid cancer, the heating properties of a ferromagnetic carbon steel rod and a prototype Ti-coated needle using this carbon steel rod, were investigated in several high-frequency outputs at 300 kHz. In the former, the heating property was drastically different among the three inclination angles (θ = 0°, 45° and 90°) relative to the magnetic flux direction as a result of the shape magnetic anisotropy. However, the effect of the inclination angles was completely eliminated in the latter. It is considered that the complete non-oriented heating property relative to the magnetic flux direction allows the precise control of the ablation temperature during minimally invasive thermotherapy without a lead-wire connected to a fiber-optic thermometer. This newly designed Ti-coated device will be suitable for clinical use combined with its superior biocompatibility for ablation treatments using high-frequency induction heating.

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Figures

Figure 1
Figure 1
Appearance of the ferromagnetic carbon steel rod (a) and the newly designed prototype Ti-coated ablation needle used in the present study (b).
Figure 2
Figure 2
Setup for measuring the heating properties of the ferromagnetic carbon steel rod and the newly designed prototype ablation needle having different inclination angles relative to the magnetic flux direction.
Figure 3
Figure 3
Changes in temperature of the ferromagnetic carbon steel rod having different inclination angles relative to the magnetic flux direction versus the induction time for the high-frequency output power of 80 W at 300 kHz.
Figure 4
Figure 4
Changes in temperature of the ferromagnetic carbon steel rod having different inclination angles relative to the magnetic flux direction versus the induction time for thehigh-frequency output power of 100 W at 300 kHz.
Figure 5
Figure 5
Changes in temperature of the prototype Ti-coated ablation needle at different inclination angles relative to the magnetic flux direction versus the induction time for the high-frequency output of 80 W at 300 kHz.
Figure 6
Figure 6
Changes in temperature of the prototype Ti-coated ablation needle at different inclination angles relative to the magnetic flux direction versus the induction time for the high-frequency output of 90 W at 300 kHz.
Figure 7
Figure 7
Changes in temperature of the prototype Ti-coated ablation needle at different inclination angles relative to the magnetic flux direction versus the induction time for the high-frequency output of 100 W at 300 kHz.
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References

    1. Matsuura M., Nakajima N., Araki K., Ito K. The usefulness of radiation therapy for hepatocellular carcinoma. Hepatogastroenterology. 1998;45:791–796. - PubMed
    1. Hawkins M.A., Dawson L.A. Radiation therapy for hepatocellular carcinoma: From palliation to cure. Cancer. 2006;106:1653–1663. doi: 10.1002/cncr.21811. - DOI - PubMed
    1. Dawson L.A. The evolving role of radiation therapy in hepatocellular carcinoma. Cancer Radio ther. 2008;12:96–101. doi: 10.1016/j.canrad.2007.12.007. - DOI - PubMed
    1. Ganne-Carrié N., Trinhet J.C. Systemic treatment of hepatocellular carcinoma. Eur. J. Gastro Enterol. Hepatol. 2004;16:275–281. doi: 10.1097/00042737-200403000-00005. - DOI - PubMed
    1. Okada S. Chemotherapy in hepatocellular carcinoma. Hepatogastroenterology. 1998;45(Suppl. 3):1259–1263. - PubMed

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