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. 2014 Dec;44(12):3063-71.
doi: 10.1007/s10803-014-2170-2.

Psychiatric comorbidity and medication use in adults with autism spectrum disorder

Tara R Buck  1 , Joseph Viskochil, Megan Farley, Hilary Coon, William M McMahon, Jubel Morgan, Deborah A Bilder
Affiliations

Psychiatric comorbidity and medication use in adults with autism spectrum disorder

Tara R Buck et al. J Autism Dev Disord. 2014 Dec.

Abstract

The purpose of this study was to investigate comorbid psychiatric disorders and psychotropic medication use among adults with autism spectrum disorder (ASD) ascertained as children during a 1980's statewide Utah autism prevalence study (n = 129). Seventy-three individuals (56.6 %) met criteria for a current psychiatric disorder; 89 participants (69.0 %) met lifetime criteria for a psychiatric disorder. Caregivers reported a psychiatric diagnosis in 44 participants (34.1 %). Anxiety disorder had the highest current and lifetime prevalence (39.5 and 52.7 %, respectively). Participants with intellectual disability (n = 94, 72.8 %) were significantly less likely to have community-based diagnoses of anxiety (χ(2) = 5.37, p = 0.02) or depression (χ(2) = 13.18, p < 0.001) reported by caregivers. Seventy-six participants (58.9 %) were taking ≥1 psychotropic medication. Comorbid psychiatric disorders occur frequently in adults with ASD, though identifying these disorders poses a challenge in community settings. A greater understanding of the presentation of these conditions within this population will increase assessment validity and the potential for efficacious intervention.

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Fig. 1
Fig. 1
Percentages of participants with a psychiatric disorder based on caregiver-report, current and lifetime Mini PAS-ADD criteria
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