Severe renal failure following high-dose ifosfamide and mesna
- PMID: 2495864
- DOI: 10.1007/BF00292414
Severe renal failure following high-dose ifosfamide and mesna
Abstract
A 62-year-old woman developed subacute renal failure after the repeated administration of ifosfamide (IFX), despite its combination with continuous sodium 2-mercaptoethane sulfonate (mesna) infusion. Biopsy findings, the possible underlying mechanism, and the existing literature are discussed.