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. 1989 May;57(5):1615-7.
doi: 10.1128/iai.57.5.1615-1617.1989.

Protection of mice against Listeria monocytogenes infection by recombinant human tumor necrosis factor alpha

J V Desiderio  1 , P A Kiener, P F Lin, G A Warr
Affiliations

Protection of mice against Listeria monocytogenes infection by recombinant human tumor necrosis factor alpha

J V Desiderio et al. Infect Immun. 1989 May.

Abstract

Recombinant human tumor necrosis factor alpha (rHuTNF-alpha) administered intravenously to mice resulted in enhanced resistance to a lethal challenge infection of Listeria monocytogenes given 24 h later. The observed protection was lost following treatment of the rHuTNF-alpha preparations with rabbit polyclonal antibody rHuTNF-alpha but not with normal rabbit immunoglobulin G.

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References

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