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. 2014 Jul;20(7):1260-2.
doi: 10.3201/eid2007.140318.

MERS-related betacoronavirus in Vespertilio superans bats, China

Li Yang, Zhiqiang Wu, Xianwen Ren, Fan Yang, Junpeng Zhang, Guimei He, Jie Dong, Lilian Sun, Yafang Zhu, Shuyi Zhang, Qi Jin

MERS-related betacoronavirus in Vespertilio superans bats, China

Li Yang et al. Emerg Infect Dis. 2014 Jul.
No abstract available

Keywords: China; MERS-CoV; MERS–related betacoronavirus; Middle East respiratory syndrome coronavirus; Middle East respiratory syndrome coronavirus–related betacoronavirus; Vespertilio superans; bat; betacoronaviruses; coronavirus; lineage; lineage C betacoronavirus; reservoir; sequencing; viruses.

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Figures

Figure
Figure
Phylogenetic trees based on the deduced amino acid sequences of the partial RNA-dependent RNA polymerase (RdRp; an 816-nt sequence fragment corresponding to positions 14817–15632 in human Middle East respiratory syndrome coronavirus [hCoV-MERS; KF192507]) and complete spike (S) protein. The novel virus is shown in gray, and hCoV-MERS is shown in bold. The following coronaviruses were used (GenBank accession numbers are shown in parentheses): severe acute respiratory syndrome coronavirus (SARS-CoV; NC004718), Bat Rp-coronavirus/Shaanxi2011(JX993987), Bat Cp-coronavirus/Yunnan2011(JX993988), Bat coronavirus HKU9-1 (BtCoV-HKU9-1; EF065513), BtCoV-133/2005(NC008315), BtCoV-HKU4-1 (EF065505), BtCoV-HKU4-2 (EF065506), BtCoV-HKU4-3 (EF065507), BtCoV-HKU4-4 (EF065508), BtCoV-HKU5-1 (EF065509), BtCoV-HKU5-2 (EF065510), BtCoV-HKU5-3 (EF065511), BtCoV-HKU5-5 (EF065512), BtCoV-ITA26/384/2012 (KF312399), BtCoV-KW2E-F82 (JX899382), BtCoV-KW2E-F93 (JX899383), BtCoV-KW2E-F53 (JX899384), BtCoV-8–724 (KC243390), BtCoV-8–691 (KC243391), BtCoV-UKR-G17 (KC243392), Human betacoronavirus 2c EMC/2012 (hCoV-MERS/EMC; JX869059), hCoV-OC43 (NC005147), hCoV-NL63 (NC005831), Betacoronavirus ErinaceusCoV/2012-174 (EriCoV-2012-174; KC545383), and EriCoV-2012-216 (KC545386). Scale bar indicates genetic distance estimated by using WAG+G model for the RdRp and WAG+G+F model for the S protein implemented in MEGA5 (http://www.megasoftware.net/).
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