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Review
. 2014 Sep;11(3):263-70.
doi: 10.1007/s11904-014-0218-8.

Vitamin D deficiency and altered bone mineral metabolism in HIV-infected individuals

Allison Ross Eckard  1 , Grace A McComsey
Affiliations
Review

Vitamin D deficiency and altered bone mineral metabolism in HIV-infected individuals

Allison Ross Eckard et al. Curr HIV/AIDS Rep. 2014 Sep.

Abstract

Although patients with HIV infection are living decades longer than before with the advent of combination antiretroviral therapy, they have an increased rate of co-morbidities associated with chronic HIV, such as osteoporosis, cardiovascular disease, and immune dysfunction. Many of these complications are known to be affected by vitamin D status in the general population. Thus, the high rate of vitamin D deficiency among HIV-infected patients is alarming. Many observational and cohort studies have demonstrated that vitamin D deficiency is associated with these HIV-related complications, but randomized, placebo-controlled trials are limited. This paper reviews recent data on vitamin D deficiency in HIV infection.

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References

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