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Case Reports
. 1989 Mar-Apr;13(2):209-13.
doi: 10.1177/0148607189013002209.

Pulmonary deposition of calcium phosphate crystals as a complication of home total parenteral nutrition

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Case Reports

Pulmonary deposition of calcium phosphate crystals as a complication of home total parenteral nutrition

J B Knowles et al. JPEN J Parenter Enteral Nutr. 1989 Mar-Apr.

Abstract

A patient on home total parenteral nutrition (TPN) developed a diffuse granulomatous interstitial pneumonitis secondary to calcium phosphate deposition. Calcium and phosphorus concentrations in the TPN formula were not unusually high, indicating that other factors contributed to calcium phosphate crystallization. The effects of duration of storage of the TPN formulation, solution temperature, pH, and magnesium concentration on calcium phosphate precipitation are discussed.

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