Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2014 Jun 24:3:e03371.
doi: 10.7554/eLife.03371.

Cheaters divide and conquer

Kirsten Bomblies  1
Affiliations
Comment

Cheaters divide and conquer

Kirsten Bomblies. Elife. .

Abstract

Three 'killer genes' in one species of fission yeast act selfishly and keep it reproductively isolated from a closely related species.

Keywords: chromosomal rearrangements; meiotic drive; recombination; speciation.

PubMed Disclaimer

Conflict of interest statement

Competing interests:The author declares that no competing interests exist.

Figures

Figure 1.
Figure 1.. Spore killers interact and determine the survival of spores from S. pombe/S. kambucha hybrids.
(A) Each chromosome in S. kambucha (K1-3) harbours a spore killer gene that works against (black lines) the corresponding chromosome in S. pombe (P1-3). Zanders et al. propose that the P3 chromosome in S. pombe contains a killer gene that works against (black line with question mark) the K3 chromosome in S. kambucha. (B) Combinations of chromosomes generated by random segregation during spore-production by the S. pombe/S. kambucha hybrid, including one aneuploid that inherits copies of chromosome 3 from both parents (bottom). Chromosome combinations predicted to yield viable spores are shown in green, and those predicted to die in yellow. Spore killers are labelled in black.
See this image and copyright information in PMC

Comment on

Similar articles

See all similar articles

Cited by

References

    1. Burt A, Trivers R. 2006. Genes in conflict: the biology of selfish genetic elements. Harvard University Press
    1. Hammond TM, Rehard DG, Xiao H, Shiu PKT. 2012. Molecular dissection of Neurospora spore killer meiotic drive elements. Proceedings of the National Academy of Sciences of the USA 109:12093–12098. doi: 10.1073/pnas.120326710 - DOI - PMC - PubMed
    1. Hurst GDD, Werren JH. 2001. The role of selfish genetic elements in eukaryotic evolution. Nature Reviews Genetics 2:597–606. doi: 10.1038/35084545 - DOI - PubMed
    1. McDermott SR, Noor MAF. 2010. The role of meiotic drive in hybrid male sterility. Philosophical Transactions of the Royal Society B 365:1265–1272. doi: 10.1098/rstb.2009.0264 - DOI - PMC - PubMed
    1. Singh G, Klar AJS. 2002. The 2.1-kb inverted repeat DNA sequences flank the mat2,3 silent region in two species of Schizosaccharomyces and are involved in epigenetic silencing in Schizosaccharomyces pombe. Genetics 162:591–602 - PMC - PubMed

MeSH terms