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. 2014 Jul;20(7):1227-30.
doi: 10.3201/eid2007.140296.

Detection and genetic characterization of deltacoronavirus in pigs, Ohio, USA, 2014

Leyi Wang, Beverly Byrum, Yan Zhang

Detection and genetic characterization of deltacoronavirus in pigs, Ohio, USA, 2014

Leyi Wang et al. Emerg Infect Dis. 2014 Jul.

Abstract

In Ohio, United States, in early 2014, a deltacoronavirus was detected in feces and intestine samples from pigs with diarrheal disease. The complete genome sequence and phylogenetic analysis of the virus confirmed that the virus is closely related to a porcine deltacoronavirus (porcine coronavirus HKU15) reported in Hong Kong in 2012.

Keywords: Coronaviridae; Deltacoronavirus genus; Ohio; United States; deltacoronavirus; diarrheal disease; genetic characterization; pig farms; piglets; pigs; sows; viruses.

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Figures

Figure 1
Figure 1
Phylogenetic tree constructed on the basis of the whole-genome sequences of virus strains from 4 coronavirus genera (Alphacoronavirus, Betacoronavirus, Gammacoronavirus, and Deltacoronavirus), including the porcine coronavirus HKU15 OH1987 strain (indicated with triangle). The dendrogram was constructed by using the neighbor-joining method in the MEGA software package, version 6.05 (http://www.megasoftware.net/). Bootstrap resampling (1,000 replications) was performed, and bootstrap values are indicated for each node. Reference sequences obtained from GenBank are indicated by strain name and accession number. Scale bar represents 0.1 nt substitutions per site. PEDV, virus and porcine epidemic diarrhea virus; PRCV, porcine respiratory coronavirus; TGEV, transmissible gastroenteritis virus; SARS, severe acute respiratory syndrome. PHEV, porcine hemagglutinating encephalomyelitis virus.
Figure 2
Figure 2
Phylogenetic analyses of spike protein (A) and nucleocapsid protein (B) of virus strains of 4 coronavirus genera (Alphacoronavirus, Betacoronavirus, Gammacoronavirus, and Deltacoronavirus), including the porcine coronavirus HKU15 OH1987 strain (indicated with triangle). The dendrogram was constructed by using the neighbor-joining method in the MEGA software package, version 6.05 (http://www.megasoftware.net/). Bootstrap resampling (1,000 replications) was performed, and bootstrap values are indicated for each node. Reference sequences obtained from GenBank are indicated by strain name and accession number. Scale bars represent 0.1 aa substitutions per site. PEDV, virus and porcine epidemic diarrhea virus; PRCV, porcine respiratory coronavirus; TGEV, transmissible gastroenteritis virus; PHEV, porcine hemagglutinating encephalomyelitis virus; SARS, severe acute respiratory syndrome.
See this image and copyright information in PMC

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