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Case Reports
. 2013 Feb 7;2013(2):rjs047.
doi: 10.1093/jscr/rjs047.

A case of metaplastic breast cancer in a man

James Geoffrey Barr  1 , Elizabeth Sarah Jane Clayton  2 , Wendy Sotheran  2
Affiliations
Case Reports

A case of metaplastic breast cancer in a man

James Geoffrey Barr et al. J Surg Case Rep. .

Abstract

Metaplastic breast cancers (MPBCs) represent <1% of breast cancers. Reports of MPBC in men are limited to case reports. We report a case of MPBC with pulmonary metastasis occurring in a 59-year-old man who initially presented with a presumed breast abscess. Histology from the breast lesion revealed a poorly differentiated carcinoma and a computed tomography scan showed an ulcerative right-sided breast mass and an area of scarring in the apex of the left lung. The breast lesion and the lung lesion were resected separately and the histology from the lung showed a poorly differentiated carcinoma with sarcomatous features in keeping with metastasis from a primary breast cancer. Our patient then proceeded to chemotherapy with FEC 100 regimen (5-fluorouracil, epirubicin and cyclophosphamide). MPBC is an aggressive breast cancer that has a propensity to metastasis to the lungs. Prognosis is poor.

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References

    1. Pezzi CM, Patel-Parekh L, Cole K, Franko J, Klimberg VS, Bland K. Characteristics and treatment of metaplastic breast cancer: analysis of 892 cases from the National Cancer Data Base. Ann Surg Oncol. 2007;14:166–73. - PubMed
    1. Rungta S, Kleer CG. Metaplastic carcinomas of the breast: diagnostic challenges and new translational insights. Arch Pathol Lab Med. 2012;136:896–900. - PMC - PubMed
    1. Kuo SH, Chen CL, Huang CS, Cheng AL. Metaplastic carcinoma of the breast: analysis of eight Asian patients with special emphasis on two unusual cases presenting with inflammatory-type breast cancer. Anticancer Res. 2000;20:2219–22. - PubMed
    1. Shah DR, Tseng WH, Martinez SR. Treatment options for metaplastic breast cancer. ISRN Oncol. 2012;70:61–62. - PMC - PubMed
    1. Carlucci M, Iacobellis M, Colonna F, Marseglia M, Gambarotti M, Giardina C, Bisceglia M. Metaplastic carcinoma of the breast with dominant squamous and sebaceous differentiation in the primary tumor and osteochondroid metaplasia in a distant metastasis: report of a case with review of sebaceous differentiation in breast tumors. Int J Surg Pathol. 2012;20:284–96. - PubMed

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