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Review
. 2015 Jan;111(1):61-5.
doi: 10.1002/jso.23697. Epub 2014 Jun 25.

Prophylactic thyroidectomy: who needs it, when, and why

Tracy S Wang  1 , Adwoa Opoku-Boateng, Sanziana A Roman, Julie Ann Sosa
Affiliations
Review

Prophylactic thyroidectomy: who needs it, when, and why

Tracy S Wang et al. J Surg Oncol. 2015 Jan.

Abstract

The most common hereditary thyroid cancer is medullary thyroid cancer, which can be associated with MEN 2A, MEN 2B, or FMTC. In these patients, prophylactic thyroidectomy is recommended; timing of surgery is dependent on the specific RET mutation. Prophylactic thyroidectomy should include total thyroidectomy and accompanying central compartment neck dissection should be done for patients at high risk for micro-metastatic disease only. Surgery should be performed at tertiary care institutions by high-volume thyroid surgeons.

Keywords: MEN 2A; MEN 2B; familial MTC; medullary thyroid cancer; prophylactic thyroidectomy.

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