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. 2014 Jun 26;510(7506):485-96.
doi: 10.1038/nature13384.

An overview of N-heterocyclic carbenes

Matthew N Hopkinson  1 , Christian Richter  1 , Michael Schedler  1 , Frank Glorius  1
Affiliations

An overview of N-heterocyclic carbenes

Matthew N Hopkinson et al. Nature. .

Abstract

The successful isolation and characterization of an N-heterocyclic carbene in 1991 opened up a new class of organic compounds for investigation. From these beginnings as academic curiosities, N-heterocyclic carbenes today rank among the most powerful tools in organic chemistry, with numerous applications in commercially important processes. Here we provide a concise overview of N-heterocyclic carbenes in modern chemistry, summarizing their general properties and uses and highlighting how these features are being exploited in a selection of pioneering recent studies.

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