Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Jun 18;7(3):446-51.
doi: 10.3980/j.issn.2222-3959.2014.03.11. eCollection 2014.

Analysis of glistenings in hydrophobic acrylic intraocular lenses on visual performance

Lei Xi  1 , Yi Liu  1 , Feng Zhao  1 , Chuan Chen  1 , Bing Cheng  1
Affiliations

Analysis of glistenings in hydrophobic acrylic intraocular lenses on visual performance

Lei Xi et al. Int J Ophthalmol. .

Abstract

Aim: To assess patients' visual performance with glistenings in one piece soft hydrophobic acrylic intraocular lenses (IOLs) (Alcon) 2 years postoperatively.

Methods: This cross section trial included 120 eyes with one piece IOL at 2 years postoperatively. Glistening was classified in 4 groups, ranging from 0 (none) to 3 (most evident) according to their severity in IOLs optics observed under a slit lamp. All eyes underwent a uncorrected and best-corrected visual acuity evaluation (UCVA and BCVA, LogMAR scale), a complete clinical examination, a contrast sensitivity (CS) evaluation by F.A.C.T chart, and a visual field test by Humphrey Field Analyzer ‖ (HFA). One-way ANOVA was used for quantitative data, while Pearson χ (2) test was used for qualitative data to analyze the visual function of 4 glistening groups.

Results: Totally 120 eyes were enrolled with 30 eyes in each glistening group. There was no statistical correlation between glistening grades and patients' age, IOLs power, postoperative UCVA and BCVA (P>0.05). Quantificationally, CS values among each group were not statistically different. However, qualitative analysis showed there were more eyes in grade 3 group than in grade 0 group having abnormally declined CS at high spatial frequency (10% vs 36.7% at 18 cpd, P=0.029; 6.7% vs 26.7% at 12 cpd, P=0.013). Mean deviation (MD) of the visual field test was -2.14±2.31, -1.97±2.23, -3.02±3.17, -4.12±3.38 in group 0 to 3 respectively. There was a significant decrease in the most serious glistenings group (P =0.018).

Conclusion: Glistenings may potentially have an impact on contrast sensitivity at high spatial frequency and MD in visual field test.

Keywords: cataract; contrast sensitivity; hydrophobic acrylic; intraocular lens; mean deviation.

PubMed Disclaimer

Figures

Figure 1
Figure 1. Examples of glistening grading. It was graded according to the number of glistenings per field (25×)
A: Grade 0 (absent); B: Grade 1 (trace); C: Grade 2 (moderate); D: Grade 3 (severe).
Figure 2
Figure 2. Association between glistening grade and IOL power.
Figure 3
Figure 3. Contrast sensitivity values among glistening grade groups
Error bars represent 95% confidence intervals. Glistening grade was not associated with contrast sensitivity (analysis of variance, P>0.1 at all spatial frequencies). Data were available for 120 eyes.
Figure 4
Figure 4. Percentage of cases with declined contrast sensitivity in each group at different frequency
Data were available for 120 eyes (Chi-square test). aThere are significant differences of cases with declined cs in group grade 3 and other groups at 12 cpd (cycle per degree). bThere are significant more cases with cs decreased in group grade 3 than the other groups at 18 cpd.
See this image and copyright information in PMC

References

    1. Anderson C, Koch DD, Green G, Patel A, van Noy S. Alcon AcrySof™ acrylic intraocular lens. In: Martin RG, Gills JP, Sanders DR, editors. Foldable Intraocular Lenses. Thorofare, Slack; 1993. pp. 161–177.
    1. Wilkins E, Olson RJ. Glistenings with long-term follow-up of the Surgidev B20/20 polymethylmethacrylate intraocular lens. Am J Ophthalmol. 2001;132(5):783–785. - PubMed
    1. Cisneros-Lanuza A, Hurtado-Sarrio M, Duch-Samper A, Gallego-Pinazo R, Menezo-Rozalen JL. Glistenings in the Artiflex phakic intraocular lens. J Cataract Refract Surg. 2007;33(8):1405–1408. - PubMed
    1. Colin J, Orignac I, Touboul D. Glistenings in a large series of hydrophobic acrylic intraocular lenses. J Cataract Refract Surg. 2009;35(12):2121–2126. - PubMed
    1. Behndig A, Monestam E. Quantification of glistenings in intraocular lenses using Scheimpflug photography. J Cataract Refract Surg. 2009;35(1):14–17. - PubMed

LinkOut - more resources