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. 2014:2014:738716.
doi: 10.1155/2014/738716. Epub 2014 May 20.

Primary surgical therapy for locally limited oral tongue cancer

Konstantinos Mantsopoulos  1 , Georgios Psychogios  1 , Julian Künzel  1 , Frank Waldfahrer  1 , Johannes Zenk  1 , Heinrich Iro  1
Affiliations

Primary surgical therapy for locally limited oral tongue cancer

Konstantinos Mantsopoulos et al. Biomed Res Int. 2014.

Abstract

Objectives: The aim of this study was to assess the efficacy of primary surgical treatment in the management of locally limited oral tongue carcinoma.

Methods: A retrospective evaluation was carried out for all patients treated with primary surgery for pT1-pT2 oral tongue carcinomas at a tertiary referral center between 1980 and 2005. All cases were assessed for disease-specific survival and local control rates in relation to T classification, N classification, infiltration depth of the primary tumor, and decision making on neck management and adjuvant therapy. The cases were additionally evaluated for the incidence of major complications and tracheotomies.

Results: 263 cases were assessed. The 5-year disease-specific survival rate was 75.2%. Positive neck disease was shown to be a significant negative prognostic factor. The occult metastasis rate was 20.2%.

Conclusions: Primary surgical treatment is a very effective modality against T1-T2 oral tongue carcinoma, and a low rate of complications can be anticipated.

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Figures

Figure 1
Figure 1
Kaplan-Meier analysis of disease-specific survival relative to T status in the group of N0 patients without adjuvant therapy.
Figure 2
Figure 2
Kaplan-Meier analysis of disease-specific survival relative to N status.
Figure 3
Figure 3
Kaplan-Meier analysis of disease-specific survival relative to infiltration depth.
See this image and copyright information in PMC

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