Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Aug 23;3(3):597-611.
doi: 10.3390/biom3030597.

Microbial enzymes with special characteristics for biotechnological applications

Affiliations

Microbial enzymes with special characteristics for biotechnological applications

Poonam Singh Nigam. Biomolecules. .

Abstract

This article overviews the enzymes produced by microorganisms, which have been extensively studied worldwide for their isolation, purification and characterization of their specific properties. Researchers have isolated specific microorganisms from extreme sources under extreme culture conditions, with the objective that such isolated microbes would possess the capability to bio-synthesize special enzymes. Various Bio-industries require enzymes possessing special characteristics for their applications in processing of substrates and raw materials. The microbial enzymes act as bio-catalysts to perform reactions in bio-processes in an economical and environmentally-friendly way as opposed to the use of chemical catalysts. The special characteristics of enzymes are exploited for their commercial interest and industrial applications, which include: thermotolerance, thermophilic nature, tolerance to a varied range of pH, stability of enzyme activity over a range of temperature and pH, and other harsh reaction conditions. Such enzymes have proven their utility in bio-industries such as food, leather, textiles, animal feed, and in bio-conversions and bio-remediations.

PubMed Disclaimer

References

    1. Pandey A., Selvakumar P., Soccol C.R., Nigam P. Solid-state fermentation for the production of industrial enzymes. Curr. Sci. 1999;77:149–162.
    1. Chirumamilla R.R., Muralidhar R., Marchant R., Nigam P. Improving the quality of industrially important enzymes by directed evolution. Mol. Cell. Biochem. 2001;224:159–168. doi: 10.1023/A:1011904405002. - DOI - PubMed
    1. Kumar C.G., Takagi H. Microbial alkaline proteases: From a bioindustrial viewpoint. Biotechnol. Adv. 1999;17:561–594. doi: 10.1016/S0734-9750(99)00027-0. - DOI - PubMed
    1. Ahmed S., Riaz S., Jamil A. Molecular cloning of fungal xylanases: An overview. Appl. Microbiol. Biotechnol. 2009;84:19–35. doi: 10.1007/s00253-009-2079-4. - DOI - PubMed
    1. Wang X., Li D., Watanabe T., Shigemori Y., Mikawa T., Okajima T., Mao L.Q., Ohsaka T. A glucose/o-2 biofuel cell using recombinant thermophilic enzymes. Int. J. Electrochem. Sci. 2012;7:1071–1078.