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Review
. 2014 Jul;10(3):471-9.
doi: 10.1016/j.hfc.2014.04.005.

Novel biomarkers in heart failure with preserved ejection fraction

Kevin S Shah  1 , Alan S Maisel  2
Affiliations
Review

Novel biomarkers in heart failure with preserved ejection fraction

Kevin S Shah et al. Heart Fail Clin. 2014 Jul.

Abstract

Heart failure with preserved ejection fraction (HFPEF) is a common subtype of heart failure with morbidity and mortality similar to that of heart failure with systolic dysfunction. This article discusses the numerous biomarkers that promise to play a substantial role in terms of our ability to understand the mechanisms of HFPEF and discern possible phenotypes that respond to targeted therapies: natriuretic peptides, high-sensitivity troponins, galectin-3, soluble ST2, neutrophil gelatinase-associated lipocalin, and cystatin C.

Keywords: Biomarkers; Diagnosis; Heart failure; Preserved ejection fraction; Prognosis.

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