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Comparative Study
. 2014 Jun 28;20(24):7926-32.
doi: 10.3748/wjg.v20.i24.7926.

Laparoscopic vs open extended right hemicolectomy for colon cancer

Li-Ying Zhao  1 , Pan Chi  1 , Wei-Xing Ding  1 , Shun-Rong Huang  1 , Si-Fen Zhang  1 , Kai Pan  1 , Yan-Feng Hu  1 , Hao Liu  1 , Guo-Xin Li  1
Affiliations
Comparative Study

Laparoscopic vs open extended right hemicolectomy for colon cancer

Li-Ying Zhao et al. World J Gastroenterol. .

Abstract

Aim: To evaluate the feasibility, safety, and oncologic outcomes of laparoscopic extended right hemicolectomy (LERH) for colon cancer.

Methods: Since its establishment in 2009, the Southern Chinese Laparoscopic Colorectal Surgical Study (SCLCSS) group has been dedicated to promoting patients' quality of life through minimally invasive surgery. The multicenter database was launched by combining existing datasets from members of the SCLCSS group. The study enrolled 220 consecutive patients who were recorded in the multicenter retrospective database and underwent either LERH (n = 119) or open extended right hemicolectomy (OERH) (n = 101) for colon cancer. Clinical characteristics, surgical outcomes, and oncologic outcomes were compared between the two groups.

Results: There were no significant differences in terms of age, gender, body mass index (BMI), history of previous abdominal surgery, tumor location, and tumor stage between the two groups. The blood loss was lower in the LERH group than in the OERH group [100 (100-200) mL vs 150 (100-200) mL, P < 0.0001]. The LERH group was associated with earlier first flatus (2.7 ± 1.0 d vs 3.2 ± 0.9 d, P < 0.0001) and resumption of liquid diet (3.6 ± 1.0 d vs 4.2 ± 1.0 d, P < 0.0001) compared to the OERH group. The postoperative hospital stay was significantly shorter in the LERH group (11.4 ± 4.7 d vs 12.8 ± 5.6 d, P = 0.009) than in the OERH group. The complication rate was 11.8% and 17.6% in the LERH and OERH groups, respectively (P = 0.215). Both 3-year overall survival [LERH (92.0%) vs OERH (84.4%), P = 0.209] and 3-year disease-free survival [LERH (84.6%) vs OERH (76.6%), P = 0.191] were comparable between the two groups.

Conclusion: LERH with D3 lymphadenectomy for colon cancer is a technically feasible and safe procedure, yielding comparable short-term oncologic outcomes to those of open surgery.

Keywords: Colon cancer; D3 lymphadenectomy; Extended right hemicolectomy; Laparoscopic surgery; Survival.

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Figures

Figure 1
Figure 1
Survival outcomes. A: Cumulative overall survival rate during a 3-year interval in the LERH and OERH groups (92.0% vs 84.4%, P = 0.209; Log-rank test); B: Cumulative disease-free survival rate during a 3-year interval in the LERH and OERH groups (84.6% vs 76.6%, P = 0.191; Log-rank test). LERH: Laparoscopic extended right hemicolectomy; OERH: Open extended right hemicolectomy.
See this image and copyright information in PMC

References

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