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. 2014 Jun 1;15(2):122-4.
doi: 10.5152/jtgga.2014.53533. eCollection 2014.

Rectus abdominalis muscle metastasis from uterine leiomyosarcoma: An unusual case and review of the literature

Tayfun Güngör  1 , Serap Akbay  2 , Hayri Aksüt  3 , Bülent Yılmaz  3
Affiliations

Rectus abdominalis muscle metastasis from uterine leiomyosarcoma: An unusual case and review of the literature

Tayfun Güngör et al. J Turk Ger Gynecol Assoc. .

Abstract

Uterine leiomyosarcoma is an aggressive malignancy. Spread to the lung, thyroid, liver, brain, pancreas, heart, duodenum, breast, vagina, submandibular gland, and bone has been reported. We describe a case of metastatic uterine leiomyosarcoma to the rectus abdominalis muscle as the first case in the literature. A 39-year-old nulligravid woman presented with a history of pelvic pain. Physical examination discovered about a 6-cm mass in the suprapubic region. She had previously undergone a hysterectomy for uterine leiomyosarcoma. Operative findings had revealed a mass measuring 4×5×6 cm located in the rectus abdominalis muscle. Abnormal mitotic figures and necrosis were evident, and uterine leiomyosarcoma was diagnosed. Uterine leiomyosarcomas are malignancies of the smooth muscle arising from the myometrium. Skeletal muscle is an uncommon site of metastasis by hematogenous spread. In conclusion, we have described a case of skeletal muscle metastasis (first case of rectus abdominalis muscle metastasis) secondary to uterine leiomyosarcoma.

Keywords: Uterine leiomyosarcoma; metastasis; rectus abdominalis muscle; skeletal muscle.

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Figures

Figure 1
Figure 1
Transvaginal ultrasound image: “A hypoechoic mass measuring 61×39 mm at the widest diameters anterior to the urinary bladder”
Figure 2
Figure 2
A photomicrograph of the pathological specimen (H&E, ×40): Metastatic leiomyosarcoma infiltrating the skeletal muscles
Figure 3
Figure 3
A photomicrograph of the pathological specimen: Uterine leiomyosarcoma (H&E, ×200): Cellular eosinophilic spindle cell tumor with nuclear atypia and mitosis
See this image and copyright information in PMC

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