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. 2014 Jun;6(6):838-44.
doi: 10.3978/j.issn.2072-1439.2014.05.08.

A propensity score analysis on the effect of on-pump versus off-pump coronary artery bypass grafting for patients with coronary artery disease

Affiliations

A propensity score analysis on the effect of on-pump versus off-pump coronary artery bypass grafting for patients with coronary artery disease

Peng Liu et al. J Thorac Dis. 2014 Jun.

Abstract

Aim: The aim of this retrospective observational study was to investigate the effect of on-pump versus off-pump coronary artery bypass grafting (CABG) for patients with coronary artery diseases (CAD).

Methods: A retrospective observational study was performed using a propensity score analysis in 290 consecutive patients undergoing CABG between April 2009 and March 2014, of them, 54 patients undergoing off-pump CABG (OPCABG) were matched with 54 patients undergoing on-pump CABG (ONCABG) by propensity score. The perioperative complications and hospital mortality were documented.

Results: Preoperative characteristics were comparable in both groups following propensity matching. Postoperative myocardial infarction (MI) incidence was lower in OPCABG group than in ONCABG group (3.7% vs. 14.8%, P=0.046); both hospital mortality and the major complications rates were similar in the two groups after propensity adjustment for preoperative characteristics.

Conclusions: The perioperative complications are similar in both off-pump and on pump CABG groups, the short-term effect of OPCABG is similar to that of ONCABG.

Keywords: Coronary artery disease (CAD); cardiopulmonary bypass (CPB); coronary artery bypass grafting (CABG); propensity score analysis.

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Figures

Figure 1
Figure 1
A female patient underwent OPCABG procedure 2.5 months earlier had chest wound dehiscence and infection (A,C), no healing of sterna wound (B) and pericardial effusion (D) demonstrated on CT scan. OPCABG, off-pump coronary artery bypass grafting.

References

    1. Takagi H, Watanabe T, Mizuno Y, et al. A meta-analysis of large randomized trials for mid-term major cardio- and cerebrovascular events following off-pump versus on-pump coronary artery bypass grafting. Interact Cardiovasc Thorac Surg 2014;18:522-4 - PMC - PubMed
    1. Ren S, Liu P, Ma G, et al. Long-term outcomes of synchronous carotid endarterectomy and coronary artery bypass grafting versus solely carotid endarterectomy. Ann Thorac Cardiovasc Surg 2012;18:228-35 - PubMed
    1. Ren S, Fan X, Peng L, et al. Expression of NF-κB, CD68 and CD105 in carotid atherosclerotic plaque. J Thorac Dis 2013;5:771-6 - PMC - PubMed
    1. Ren S, Li X, Wen J, et al. Systematic review of randomized controlled trials of different types of patch materials during carotid endarterectomy. PLoS One 2013;8:e55050. - PMC - PubMed
    1. Hattler B, Messenger JC, Shroyer AL, et al. Off-Pump coronary artery bypass surgery is associated with worse arterial and saphenous vein graft patency and less effective revascularization: Results from the Veterans Affairs Randomized On/Off Bypass (ROOBY) trial. Circulation 2012;125:2827-35 - PubMed