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. 2014 Oct;18(10):1864-87.
doi: 10.1007/s10461-014-0827-7.

Systematic review of couple-based HIV intervention and prevention studies: advantages, gaps, and future directions

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Systematic review of couple-based HIV intervention and prevention studies: advantages, gaps, and future directions

Tina Jiwatram-Negrón et al. AIDS Behav. 2014 Oct.

Abstract

We conducted a systematic review of couple-based HIV biobehavioral (skills-building, VCT, and adherence) and biomedical (ART, circumcision) prevention and intervention studies designed to reduce sexual- and drug-risk behaviors and HIV transmission and acquisition. Of the 11,162 papers identified in the search, 93 peer-reviewed papers met the inclusion criteria and yielded a total of 33 studies conducted globally. Biobehavioral couple-based prevention and intervention studies have been efficacious in reducing sexual- and drug-risk behaviors, increasing access to HIV testing and care, and improving adherence. Biomedical couple-based studies were found to reduce HIV incidence among HIV-negative sex partners and viral load among HIV-positive partners. Despite much progress, couple-based HIV prevention and intervention studies remain limited; a number of methodological gaps exist and studies focusing on MSM, people who inject drugs, and sex workers are scarce.

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Conflict of interest statement

Conflict of interest

The authors have no conflicts of interest.

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Fig. 1
Flow diagram of systematic review search process

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