Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Oct;18(10):1864-87.
doi: 10.1007/s10461-014-0827-7.

Systematic review of couple-based HIV intervention and prevention studies: advantages, gaps, and future directions

Tina Jiwatram-Negrón  1 , Nabila El-Bassel
Affiliations

Systematic review of couple-based HIV intervention and prevention studies: advantages, gaps, and future directions

Tina Jiwatram-Negrón et al. AIDS Behav. 2014 Oct.

Abstract

We conducted a systematic review of couple-based HIV biobehavioral (skills-building, VCT, and adherence) and biomedical (ART, circumcision) prevention and intervention studies designed to reduce sexual- and drug-risk behaviors and HIV transmission and acquisition. Of the 11,162 papers identified in the search, 93 peer-reviewed papers met the inclusion criteria and yielded a total of 33 studies conducted globally. Biobehavioral couple-based prevention and intervention studies have been efficacious in reducing sexual- and drug-risk behaviors, increasing access to HIV testing and care, and improving adherence. Biomedical couple-based studies were found to reduce HIV incidence among HIV-negative sex partners and viral load among HIV-positive partners. Despite much progress, couple-based HIV prevention and intervention studies remain limited; a number of methodological gaps exist and studies focusing on MSM, people who inject drugs, and sex workers are scarce.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest

The authors have no conflicts of interest.

Figures

Fig. 1
Fig. 1
Flow diagram of systematic review search process
See this image and copyright information in PMC

References

    1. UNAIDS. Global Report: UNAIDS Report on the Global AIDS Epidemic 2012, Joint United Nations Programme on HIV/AIDS. UNAIDS;
    1. Beyrer C, Abdool Karim Q. The changing epidemiology of HIV in 2013. Curr Opin HIV AIDS. 2013;8(4):306. - PubMed
    1. UNAIDS. UN World AIDS Day Report: 2012. Geneva: UNAIDS; 2012.
    1. Baral S, et al. Burden of HIV among female sex workers in low-income and middle-income countries: a systematic review and meta-analysis. Lancet Infect Dis. 2012;12(7):538–49. - PubMed
    1. Seear K, et al. Rethinking safety and fidelity: the role of love and intimacy in Hepatitis C transmission and prevention. Health Soc Rev. 2012;21(3):272–86.

Publication types