Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2008 Autumn;5(2-3):e95-e103.
doi: 10.1016/j.ddtec.2009.01.002.

Intracellular delivery of protein and peptide therapeutics

Vladimir Torchilin  1
Affiliations

Intracellular delivery of protein and peptide therapeutics

Vladimir Torchilin. Drug Discov Today Technol. 2008 Autumn.

Abstract

Many proteins and peptides are used as highly specific and effective therapeutic agents. Their use is, however, complicated by their instability and side effects. Because many protein and peptide drugs have their therapeutic targets inside cells, there is also an important task to bring these drugs into target cells without subjecting them to the lysosomal degradation. This review describes current approaches to the intracellular delivery of protein and peptide drugs. Various drug delivery systems and methods are considered allowing for safe and effective transport of protein and peptide drugs into the cell cytoplasm.:

PubMed Disclaimer

LinkOut - more resources