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Randomized Controlled Trial
. 2014 Sep;58(9):5598-601.
doi: 10.1128/AAC.02435-13. Epub 2014 Jun 30.

Preliminary study of colistin versus colistin plus fosfomycin for treatment of carbapenem-resistant Acinetobacter baumannii infections

Rujipas Sirijatuphat  1 , Visanu Thamlikitkul  2
Affiliations
Randomized Controlled Trial

Preliminary study of colistin versus colistin plus fosfomycin for treatment of carbapenem-resistant Acinetobacter baumannii infections

Rujipas Sirijatuphat et al. Antimicrob Agents Chemother. 2014 Sep.

Abstract

Ninety-four patients infected with carbapenem-resistant Acinetobacter baumannii were randomized to receive colistin alone or colistin plus fosfomycin for 7 to 14 days. The patients who received combination therapy had a significantly more favorable microbiological response and a trend toward more favorable clinical outcomes and lower mortality than those who received colistin alone. (This study has been registered at ClinicalTrials.gov under registration no. NCT01297894.).

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References

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