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. 2014 Sep;58(9):5606-8.
doi: 10.1128/AAC.02818-13. Epub 2014 Jun 30.

NDM-5 carbapenemase-encoding gene in multidrug-resistant clinical isolates of Escherichia coli from Algeria

Asma Sassi  1 , Lotfi Loucif  2 , Sushim Kumar Gupta  3 , Mazouz Dekhil  4 , Houria Chettibi  5 , Jean-Marc Rolain  6
Affiliations

NDM-5 carbapenemase-encoding gene in multidrug-resistant clinical isolates of Escherichia coli from Algeria

Asma Sassi et al. Antimicrob Agents Chemother. 2014 Sep.

Abstract

Here, we report the first autochthonous cases of infections caused by blaNDM-5 New Delhi metallo-β-lactamase-producing Escherichia coli strains recovered from urine and blood specimens of three patients from Algeria between January 2012 and February 2013. The three isolates belong to sequence type 2659 and they coexpress blaCTX-M-15 with the blaTEM-1 and blaaadA2 genes.

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Figures

FIG 1
FIG 1
Geographic distribution of NDM variants detected worldwide.
FIG 2
FIG 2
Concatenated phylogenetic tree showing the molecular relationships of the seven genes analyzed (adk, fumC, icd, purA, gyrB, recA, and mdh) for 33 clinical E. coli isolates, including the three NDM-5-positive isolates. Gray circles indicate E. coli strains belonging to sequence type 2659. The number shown at each node indicates the bootstrap level from 500 replicates.
See this image and copyright information in PMC

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