Group A streptococcal pyrogenic exotoxin (scarlet fever toxin) type A and blastogen A are the same protein
- PMID: 2498210
- PMCID: PMC313370
- DOI: 10.1128/iai.57.6.1865-1867.1989
Group A streptococcal pyrogenic exotoxin (scarlet fever toxin) type A and blastogen A are the same protein
Abstract
Group A streptococcal pyrogenic exotoxins A, B, and C (also known as scarlet fever toxins and erythrogenic toxins) were evaluated for relatedness to another streptococcus-derived lymphocyte mitogen, blastogen A. Streptococcal pyrogenic exotoxin A and blastogen A were immunologically cross-reactive and shared the same molecular weight, N-terminal amino acid sequence, and capacity to stimulate rabbit splenocyte proliferation nonspecifically.
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