Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2014 May-Jun;46(3):337-8.
doi: 10.4103/0253-7613.132191.

Overdose of mycophenolate mofetil managed in a secondary care hospital in South India

Reginald Alex  1 , Minu Mathew  2 , Sivanandan Arul  2 , Abhilash Kundavaram  1
Affiliations
Case Reports

Overdose of mycophenolate mofetil managed in a secondary care hospital in South India

Reginald Alex et al. Indian J Pharmacol. 2014 May-Jun.

Abstract

Mycophenolate mofetil (MMF) is a commonly used immunosuppressive agent and is considered relatively safe with minimal side-effects in therapeutic doses. However, data regarding the effects of an overdose is sparse and therefore, concerns remain regarding its safety. Here, we report the case of a 24-year-old young woman who consumed high dose (10 g) of MMF with suicidal intent. We did not observe any complications related to MMF overdose.

Keywords: Mycophenolate mofetil; overdose; safety.

PubMed Disclaimer

Conflict of interest statement

Conflict Interest: No

References

    1. Halloran PF. Immunosuppressive drugs for kidney transplantation. N Engl J Med. 2004;351:2715–29. - PubMed
    1. Bullingham RE, Nicholls AJ, Kamm BR. Clinical pharmacokinetics of mycophenolate mofetil. Clin Pharmacokinet. 1998;34:429–55. - PubMed
    1. Sokumbi O, el-Azhary RA, Langman LJ. Therapeutic dose monitoring of mycophenolate mofetil in dermatologic diseases. J Am Acad Dermatol. 2013;68:36–40. - PubMed
    1. Jeong H, Kaplan B. Therapeutic monitoring of mycophenolate mofetil. Clin J Am Soc Nephrol. 2007;2:184–91. - PubMed
    1. Bebarta VS, Heard K, Nadelson C. Lack of toxic effects following acute overdose of cellcept (mycophenolate mofetil) J Toxicol Clin Toxicol. 2004;42:917–9. - PubMed

Publication types