Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014:2014:872608.
doi: 10.1155/2014/872608. Epub 2014 May 29.

Frequency and clinical manifestations of dengue in urban medellin, Colombia

Berta Nelly Restrepo  1 , Mark E Beatty  2 , Yenny Goez  1 , Ruth E Ramirez  1 , G William Letson  3 , Francisco J Diaz  4 , Leidy Diana Piedrahita  1 , Jorge E Osorio  5
Affiliations

Frequency and clinical manifestations of dengue in urban medellin, Colombia

Berta Nelly Restrepo et al. J Trop Med. 2014.

Abstract

A dengue fever surveillance study was conducted at three medical facilities located in the low-income district of San Javier in Medellin, Colombia. During March 2008 to 2009, 781 patients with fever regardless of chief complaint were recruited for acute dengue virus infection testing. Of the 781 tested, 73 (9.3%) were positive for dengue infection. Serotypes DENV-2 (77%) and -3 (23%) were detected by PCR. One patient met the diagnostic criteria for dengue hemorrhagic fever. Only 3 out of 73 (4.1%) febrile subjects testing positive for dengue infection were diagnosed with dengue fever by the treating physician. This study confirms dengue virus as an important cause of acute febrile illness in Medellin, Colombia, but it is difficult to diagnose without dengue diagnostic testing.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Number of febrile patients included in the study and dengue virus diagnostic results, by month, Medellin, Colombia, March 2008-2009 (n = 781).
See this image and copyright information in PMC

References

    1. World Health Organization. Special Programme for Research and Training in Tropical Diseases (TDR) 2009. (Dengue Guidelines for Diagnosis, Treatment, Prevention and Control).
    1. Martina BEE, Koraka P, Osterhaus ADME. Dengue virus pathogenesis: an integrated view. Clinical Microbiology Reviews. 2009;22(4):564–581. - PMC - PubMed
    1. Brathwaite DO, San Martin JL, Montoya RH, del Diego J, Zambrano B, Dayan GH. The history of dengue outbreaks in the Americas. The American Journal of Tropical Medicine & Hygiene. 2012;87(4):584–593. - PMC - PubMed
    1. Beatty ME, Stone A, Fitzsimons DW, et al. Best practices in dengue surveillance: a report from the asia-pacific and americas dengue prevention boards. PLoS Neglected Tropical Diseases. 2010;4(11, article e890) - PMC - PubMed
    1. Lanciotti RS, Calisher CH, Gubler DJ, Chang G-J, Vorndam AV. Rapid detection and typing of dengue viruses from clinical samples by using reverse transcriptase-polymerase chain reaction. Journal of Clinical Microbiology. 1992;30(3):545–551. - PMC - PubMed

LinkOut - more resources