Review
Von Willebrand factor and von Willebrand's disease: a complex protein and a complex disease
Affiliations
- PMID: 2499240
Item in Clipboard
Review
Von Willebrand factor and von Willebrand's disease: a complex protein and a complex disease
Ann Clin Lab Sci.
1989 May-Jun.
Abstract
Von Willebrand factor is a complex protein which is important in several ways for normal hemostasis. Von Willebrand's disease results when there is either a quantitative or qualitative disorder of von Willebrand factor. In this review, the structure and function of von Willebrand factor are discussed. Additionally, the current laboratory and clinical classification of von Willebrand's disease and closely related variants are outlined.
Similar articles
-
Platelet adhesion to collagen in subtypes of type I von Willebrand's disease is dependent on platelet von Willebrand factor.Thromb Haemost. 1990 Oct 22;64(2):227-31. Thromb Haemost. 1990. PMID: 2125373
-
von Willebrand factor: its function and its measurement in the laboratory.Br J Biomed Sci. 1995 Mar;52(1):50-7. Br J Biomed Sci. 1995. PMID: 7549606 Review.
-
[von Willebrand syndrome].Behring Inst Mitt. 1986 Feb;(79):12-23. Behring Inst Mitt. 1986. PMID: 3487311 German.
-
von Willebrand's Disease.Clin Haematol. 1983 Feb;12(1):175-200. Clin Haematol. 1983. PMID: 6404576 Review. No abstract available.
-
Quantitative assay of a plasma factor deficient in von Willebrand's disease that is necessary for platelet aggregation. Relationship to factor VIII procoagulant activity and antigen content.J Clin Invest. 1973 Nov;52(11):2708-16. doi: 10.1172/JCI107465. J Clin Invest. 1973. PMID: 4542944 Free PMC article.
Cited by
-
Immunohistochemical evidence for the heterogeneity of maternal and fetal vascular endothelial cells in human full-term placenta.Cell Tissue Res. 1993 Nov;274(2):211-8. doi: 10.1007/BF00318740. Cell Tissue Res. 1993. PMID: 7505718