Comment
doi: 10.1182/blood-2014-05-572917.
CDK6, a new target in MLL-driven leukemia
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- PMID: 24993876
- DOI: 10.1182/blood-2014-05-572917
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Comment
CDK6, a new target in MLL-driven leukemia
Blood.
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Free article
Abstract
In this issue of Blood, Placke et al identify the cell-cycle regulator CDK6 as a promising new target in mixed lineage leukemia (MLL)-rearranged acute myeloid leukemia (AML) and show that its downregulation or pharmacological inhibition leads to growth inhibition and differentiation of MLL-driven leukemic cells.
Comment on
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Requirement for CDK6 in MLL-rearranged acute myeloid leukemia.Blood. 2014 Jul 3;124(1):13-23. doi: 10.1182/blood-2014-02-558114. Epub 2014 Apr 24. Blood. 2014. PMID: 24764564 Free PMC article.
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