Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 May 15;7(5):1410-6.
eCollection 2014.

A new classification system for pregnancy prognosis of tubal factor infertility

Shi-En Zou  1 , Yi Jin  1 , Yi-Ling Ko  1 , Jin Zhu  1
Affiliations

A new classification system for pregnancy prognosis of tubal factor infertility

Shi-En Zou et al. Int J Clin Exp Med. .

Abstract

The aim of the present study was to assess the objectivity and accuracy of a new system to evaluate pregnancy prognosis in tubal factor infertility (TFI) patients. Retrospective study in 469 TFI patients were pre- and postoperatively scored using the new system as mild, moderate or severe TFI, based on tubal adhesions, patency, morphology and structure. Follow-up was assessed to determine pregnancy outcomes. Laparoscopic salpingoplasty and hydrotubation, hysteroscopic-laparoscopic salpingoplasty and hydrotubation, and laparoscopic hydrotubation all decreased TFI scores to a similar extent. The pre- and postoperative TFI classification was significantly associated with intrauterine pregnancy (mild: 43.6% vs. moderate: 34.0% vs. severe: 19.4%, P < 0.0001) and live births (mild: 35.9% and moderate: 31.5% vs. severe: 16.8%, P = 0.0002) rates. Multivariate analysis showed that the preoperative disease course (P = 0.02), preoperative TFI score (P < 0.0001), and postoperative TFI score (P = 0.0007) were independently associated with the rate of intrauterine pregnancy rate. Multivariate analysis also showed that the postoperative TFI score (P = 0.001), pelvic inflammatory disease (P = 0.03) and age (P = 0.03) were independently associated with the rate of live births.

Conclusion: We devised a new classification system for TFI prognosis. Salpingoplasty improved these scores. Both pre- and postoperative TFI assessments using this new system are associated with pregnancy prognosis in TFI patients.

Keywords: Tubal factor infertility; follow-up; retrospective analysis; salpingoplasty; tubal classification system.

PubMed Disclaimer

References

    1. Miller JH, Weinberg RK, Canino NL, Klein NA, Soules MR. The pattern of infertility diagnoses in women of advanced reproductive age. Am J Obstet Gynecol. 1999;181:952–957. - PubMed
    1. Guzick DS, Silliman NP, Adamson GD, Buttram VC Jr, Canis M, Malinak LR, Schenken RS. Prediction of pregnancy in infertile women based on the American Society for Reproductive Medicine’s revised classification of endometriosis. Fertil Steril. 1997;67:822–829. - PubMed
    1. Hulka JF, Omran K, Berger GS. Classification of adnexal adhesions: a proposal and evaluation of its prognostic value. Fertil Steril. 1978;30:661–665. - PubMed
    1. Rutherford AJ, Jenkins JM. Hull and Rutherford classification of infertility. Hum Fertil (Camb) 2002;5:S41–45. - PubMed
    1. Caspi E, Halperin Y, Bukovsky I. The importance of periadnexal adhesions in tubal reconstructive surgery for infertility. Fertil Steril. 1979;31:296–300. - PubMed

LinkOut - more resources