Chromosomal instability, aneuploidy, and cancer
- PMID: 24995162
- PMCID: PMC4062911
- DOI: 10.3389/fonc.2014.00161
Chromosomal instability, aneuploidy, and cancer
Keywords: anaphase; aneuploidy; centrosomes; chromatin; chromosomal instability; microtubules; mitosis; spindle.
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References
-
- Boveri T. Über mehrpolige Mitosen als Mittel zur Analyse des Zellkerns. Stuber (1903)
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