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. 2016 Jan;38(1):15-20.
doi: 10.1002/hed.23838. Epub 2015 Jan 27.

Value of narrow band imaging in the early diagnosis of laryngeal cancer

Marcel Kraft  1 , Karolos Fostiropoulos  1 , Nicolas Gürtler  2 , André Arnoux  3 , Nikolaos Davaris  4 , Christoph Arens  4
Affiliations

Value of narrow band imaging in the early diagnosis of laryngeal cancer

Marcel Kraft et al. Head Neck. 2016 Jan.

Abstract

Background: Narrow band imaging (NBI) is a new imaging technique for the depiction of tumor-specific neoangiogenesis. The purpose of the present study was to assess the value of NBI in the early diagnosis of laryngeal cancer.

Methods: This prospective study includes 205 consecutive patients with a laryngeal lesion scheduled for microlaryngoscopy. NBI was immediately performed after white light endoscopy (WLE), whereas excisional biopsy was carried out for histologic verification of diagnosis.

Results: In identifying laryngeal cancer and its precursor lesions, NBI with WLE showed a significantly higher sensitivity (97% vs 79%) and accuracy (97% vs 90%) than WLE alone, but the specificity (96% vs 95%) was essentially equal in both methods.

Conclusion: NBI qualifies for rapid detection and delineation of suspicious lesions. Additionally, this noninvasive method is also beneficial in a variety of benign lesions.

Keywords: cancer; diagnostic imaging; dysplasia; endoscopy; indirect laryngoscopy; laryngology; larynx; narrow band imaging; vocal fold.

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