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Review
. 2014 Jun 30;57(8):481-508.
doi: 10.1002/jlcr.3212. Epub 2014 Jul 3.

Synthetic methodologies in organic chemistry involving incorporation of [¹⁷O] and [¹⁸O] isotopes

Vassiliki Theodorou  1 , Konstantinos Skobridis, Dimitrios Alivertis, Ioannis P Gerothanassis
Affiliations
Review

Synthetic methodologies in organic chemistry involving incorporation of [¹⁷O] and [¹⁸O] isotopes

Vassiliki Theodorou et al. J Labelled Comp Radiopharm. .

Abstract

This review is a critical survey of the literature that aims to highlight the most significant developments on synthetic strategies involving stable oxygen isotopes ([(17)O] and [(18)O]). The labeling methodologies are categorized in groups, according to the oxygen-containing functional group.

Keywords: [17O]; [18O] enrichment; labeled compound; oxygen isotopes; synthesis.

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