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. 2014 Jul 6:20:1151-4.
doi: 10.12659/MSM.890472.

Serum adenosine deaminase activity in cutaneous anthrax

Mahmut Sunnetcioglu  1 , Sevdegul Karadas  2 , Mehmet Aslan  1 , Mehmet Resat Ceylan  1 , Halit Demir  3 , Mehmet Resit Oncu  2 , Mustafa Kasım Karahocagil  1 , Aysel Sunnetcioglu  4 , Cenk Aypak  5
Affiliations

Serum adenosine deaminase activity in cutaneous anthrax

Mahmut Sunnetcioglu et al. Med Sci Monit. .

Abstract

Background: Adenosine deaminase (ADA) activity has been discovered in several inflammatory conditions; however, there are no data associated with cutaneous anthrax. The aim of this study was to investigate serum ADA activity in patients with cutaneous anthrax.

Material and methods: Sixteen patients with cutaneous anthrax and 17 healthy controls were enrolled. We measured ADA activity; peripheral blood leukocyte, lymphocyte, neutrophil, and monocyte counts; erythrocyte sedimentation rate; and C reactive protein levels.

Results: Serum ADA activity was significantly higher in patients with cutaneous anthrax than in the controls (p<0.001). A positive correlation was observed between ADA activity and lymphocyte counts (r=0.589, p=0.021) in the patient group.

Conclusions: This study suggests that serum ADA could be used as a biochemical marker in cutaneous anthrax.

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