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. 2014 Aug 15;24(16):4026-30.
doi: 10.1016/j.bmcl.2014.06.004. Epub 2014 Jun 11.

Insecticidal quinoline and isoquinoline isoxazolines

Ming Xu  1 , Ty Wagerle  2 , Jeffrey K Long  2 , George P Lahm  2 , James D Barry  2 , Rejane M Smith  2
Affiliations

Insecticidal quinoline and isoquinoline isoxazolines

Ming Xu et al. Bioorg Med Chem Lett. .

Abstract

A series of quinoline and isoquinoline isoxazolines have been designed as pesticides for crop protection. Herein we reported the chemical synthesis, biological activity and structure-activity relationships. The isoquinoline derivative, such as 3i, is discovered as potent new class of isoxazoline insecticide which is competitive with commercial insecticide Indoxacarb.

Keywords: Insecticide; Isoquinoline; Isoxazoline; Quinoline.

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