Guidance for National Tuberculosis Programmes on the Management of Tuberculosis in Children
- PMID: 24999516
- Bookshelf ID: NBK214448
Guidance for National Tuberculosis Programmes on the Management of Tuberculosis in Children
Excerpt
It is estimated that one third of the world’s population is infected with Mycobacterium tuberculosis (the bacterium that causes tuberculosis (TB)), and that each year, about 9 million people develop TB, of whom about 2 million die. Of the 9 million annual TB cases, about 1 million (11%) occur in children (under 15 years of age). Of these childhood cases, 75% occur annually in 22 high-burden countries that together account for 80% of the world’s estimated incident cases.
In countries worldwide, the reported percentage of all TB cases occurring in children varies from 3% to more than 25%. The Stop TB Strategy, which builds on the DOTS strategy developed by the World Health Organization (WHO) and the International Union Against TB and Lung Disease, has a critical role in reducing the worldwide burden of disease and thus in protecting children from infection and disease.
The management of children with TB should be in line with the Stop TB Strategy, taking into consideration the particular epidemiology and clinical presentation of TB in children. These consensus guidelines were produced to help the National Tuberculosis Programmes on the management of tuberculosis in children.
Copyright © World Health Organization 2014.
Sections
- Preface
- Declarations of Interest
- Acknowledgements
- Abbreviations and acronyms
- Definitions and distinctions
- Executive summary
- 1. Introduction
- 2. Methodology
- 3. Diagnosis of TB in children
- 4. Treatment of TB in children
- 5. Prevention of TB in children
- 6. Management of TB in children living with HIV
- 7. Management of drug-resistant TB in children
- 8. Implementation and management by NTP; integrated care
- 9. Suggestions for future research
- Annex 1 Summary of evidence and considerations underlying the recommendations
- Annex 2 TB case and treatment outcome definitions
- Annex 3 Administering, reading and interpreting a tuberculin skin test
- Annex 4 Procedures for obtaining clinical samples for smear microscopy
- Annex 5 Interim guidelines for treatment of TB in young children (less than 25 kg) using currently available FDCs (RHZ 60/30/150) and dosages achieved per weight
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