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. 2014 Feb 25;15(2):106.
doi: 10.1186/gb4162.

Insecticide resistance comes of age

Richard H Ffrench-Constant

Insecticide resistance comes of age

Richard H Ffrench-Constant. Genome Biol. .

Abstract

A new study integrates biochemistry, genetics and structural biology to reveal the mechanism of metabolic resistance in a vector mosquito in unprecedented detail.

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References

    1. ffrench-Constant RH. The molecular genetics of insecticide resistance. Genetics. 2013;194:807–815. doi: 10.1534/genetics.112.141895. - DOI - PMC - PubMed
    1. Riveron JM, Yunta C, Ibrahim SS, Djouaka R, Irving H, Menze BD, Ismail HM, Hemingway J, Ranson H, Albert A, Wondji CS. A single mutation in the GSTe2 gene allows tracking of metabolically based insecticide resistance in a major malaria vector. Genome Biol. 2014;15:R27. - PMC - PubMed
    1. Claudianos C, Russell RJ, Oakeshott JG. The same amino acid substitution in orthologous esterases confers organophosphate resistance on the house fly and a blowfly. Insect Biochem Mol Biol. 1999;29:675–686. doi: 10.1016/S0965-1748(99)00035-1. - DOI - PubMed
    1. Campbell PM, Newcomb RD, Russell RJ, Oakeshott JG. Two different amino acid substitutions in the ali-esterase, E3, confer alternative types of organophosphorus insecticide resistance in the sheep blowfly, Lucilia cuprina. Insect Biochemistry Mol Biol. 1998;28:139–150. doi: 10.1016/S0965-1748(97)00109-4. - DOI
    1. ffrench-Constant RH, Daborn PJ, Yen JL, Bogwitz MR, Le Goff G, Feil E, Jeffers S, Tijet N, Perry T, Heckel D, Batterham P, Feyereisen R, Wilson TG. A single P450 allele associated with insecticide resistance in Drosophila. Science. 2002;297:2253–2256. doi: 10.1126/science.1074170. - DOI - PubMed